Per Gregory Sadler from this April 2017 article:
First, the Stoic ideal of “living in accordance with nature” does involve adapting oneself to “nature” in the sense of the cosmos, of which any given person is merely one part of a much greater whole. Just as important, however, is realizing distinctively human, rational nature in oneself.
Second, as living beings, humans are driven by the same natural impulse for self-preservation as are other non-rational living beings. Our rationality may often be used in the service of this impulse, but that is not its only function. Integral to that rationality, as it develops, is a capacity and desire for living together harmoniously with other people. Rational human nature involves sociability.
Third, human rationality affords us the capacity to be to some extent self-determining. We can rationally reshape what it is that nature has bestowed upon us, for instance our impulses. We not only have capacities for responding to and modifying our natural environment, but also for working upon our own selves, as well as for taking part in complex human communities.
Fourth, living in accordance with nature involves the cultivation of the virtues – specifically prudence, justice, courage, and temperance – since virtue is the end to which nature orients rational beings. Doing so follows out and refines desires and impulses that we possess as human beings, for example for understanding truth, or for realizing justice.
Fifth, recognizing and fulfilling our duties is a main way in which we live in accordance with nature. This is not just a matter of blind or mechanical obedience to demands imposed upon us from outside, but rather ways in which we apply our human rationality to ourselves, others, and the situations in which we live together.